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Research Interests

Research studies where Mr Shah or Mrs Shah have been Principle Investigators

Randomised Evaluation of COVID-19 Therapy (RECOVERY)

The trial has been endorsed by the Chief Medical Officer and NHS England
Medical Director. Inclusion of pregnant and postpartum women has been endorsed by NHS England, the Royal College of Obstetricians and Gynaecologists, Royal College of Midwives, Royal College of Physicians, Tommy’s Charity, British Maternal and Fetal Medicine Society, Macdonald Obstetric Medicine Society, the Neonatal Society, the Reproductive Health and Childbirth Specialty Group Lead (NIHR Clinical Research Network).

Pregnancy and Neonatal outcomes in COVID-19

Pregnancy and Neonatal Outcomes in COVID-19: A global registry of women with suspected or confirmed SARS-CoV- 2 infeciton in pregnancy and their neonates, understanding natural history to guide treatment and prevention

Treatment of prolapse with self-care pessary: the TOPSY trial

A multi-centre randomised controlled trial , with process evaluation, to test the clinical and cost-effectiveness of self-management of vaginal pessaries to treat pelvic organ prolapse, compared to standard care to improve women's quality of life


Induction of labour for predicted macrosomia: the Big Baby trial

Difficulty in delivering the shoulders of a baby after the head has been delivered can be a serious complication during birth. Most babies that get into such trouble are larger than average. It has been suggested that if we can predict by ultrasound scan in the last weeks of pregnancy which babies are large and at increased risk, then we could deliver them a week or so earlier and reduce the chance of such complications. However, the available evidence is not clear, and can be interpreted in different ways. The aim of this study is to find out whether delivering large babies earlier is the right thing to do for baby and mother. 


A Prospective, Multi-Center Evaluation of the ENSEAL X1 Large Jaw Tissue Sealer

This prospective, single-arm, multi-center, evaluation will collect clinical data in a post-market setting. The three types of procedures studied will be colectomy, gynaecological, and thoracic. Investigators will perform each procedure using the device in compliance with their standard surgical approach and the ENSEAL X1 instructions for use.

Completed October 2019

The PRE-EMPT Trial: Preventing Recurrence of Endometriosis by Means of long acting Progestogen Therapy

PRE-EMPT is a randomised multicentre trial to compare medical treatments to prevent recurrence of disease following surgical removal of endometriosis.


GaPP 2 Trial

A multi-centre randomised controlled trial of the efficacy and mechanism of action of gabapentin for the management of chronic pelvic pain in women 

A double blind randomised controlled trial. 300 participants to recruit over 21 months. (306 participants were recruited over 41 months) Completed

Phase 3 Retrospective Trial for Ulipristal Acetate in Fibroids

International Multicentre Trial


Research Interests: Text
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